BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression
Germ-line mutations in breast cancer susceptibility gene 1 (<i>BRCA1</i>) predominantly predispose women to breast and ovarian cancers. BRCA1 is best known for its functions in maintenance of genomic integrity including repairing DNA double-strand breaks through homologous recombination...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-12-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/10/12/513 |