Dimethylsulfoxide Inhibits Oligodendrocyte Fate Choice of Adult Neural Stem and Progenitor Cells

Dimethylsulfoxide Inhibits Oligodendrocyte Fate Choice of Adult Neural Stem and Progenitor Cells

Several clinical trials address demyelinating diseases via transplantation of mesenchymal stromal cells (MSCs). Published reports detail that administration of MSCs in patients may provide a beneficial immunomodulation, and that factors secreted by MSCs are potent inducers of oligodendrogenesis. Dim...

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Bibliographic Details
Main Authors: Anna O’Sullivan, Simona Lange, Peter Rotheneichner, Lara Bieler, Ludwig Aigner, Francisco J. Rivera, Sebastien Couillard-Despres
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neuroscience
Subjects:
oligodendrogenesis
neural stem cells
myelination
DMSO
Id2
Olig2
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01242/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01242/full

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