A Next-Generation Sequencing-Based Approach to Identify Genetic Determinants of Antibiotic Resistance in Cambodian <i>Helicobacter pylori</i> Clinical Isolates

A Next-Generation Sequencing-Based Approach to Identify Genetic Determinants of Antibiotic Resistance in Cambodian <i>Helicobacter pylori</i> Clinical Isolates

We evaluated the primary resistance of <i>Helicobacter pylori</i> (<i>H. pylori</i>) to routinely used antibiotics in Cambodia, an unexplored topic in the country, and assessed next-generation sequencing&#8217;s (NGS) potential to discover genetic resistance determinants....

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Bibliographic Details
Main Authors: Vo Phuoc Tuan, Dou Narith, Evariste Tshibangu-Kabamba, Ho Dang Quy Dung, Pham Thanh Viet, Sin Sokomoth, Tran Thanh Binh, Sok Sokhem, Tran Dinh Tri, Seng Ngov, Pham Huu Tung, Ngo Phuong Minh Thuan, Tran Cong Truc, Bui Hoang Phuc, Takashi Matsumoto, Kartika Afrida Fauzia, Junko Akada, Tran Thi Huyen Trang, Yoshio Yamaoka
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Journal of Clinical Medicine
Subjects:
<i>Helicobacter pylori</i>
mutation
antibiotic resistance
next-generation sequencing
genetic determinants
whole genome sequence
Online Access:https://www.mdpi.com/2077-0383/8/6/858

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https://www.mdpi.com/2077-0383/8/6/858

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