NDK Interacts with FtsZ and Converts GDP to GTP to Trigger FtsZ Polymerisation--A Novel Role for NDK.

Nucleoside diphosphate kinase (NDK), conserved across bacteria to humans, synthesises NTP from NDP and ATP. The eukaryotic homologue, the NDPK, uses ATP to phosphorylate the tubulin-bound GDP to GTP for tubulin polymerisation. The bacterial cytokinetic protein FtsZ, which is the tubulin homologue, a...

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Bibliographic Details
Main Authors: Saurabh Mishra, Kishor Jakkala, Ramanujam Srinivasan, Muthu Arumugam, Raghavendra Ranjeri, Prabuddha Gupta, Haryadi Rajeswari, Parthasarathi Ajitkumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4668074?pdf=render