Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes.

Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes.

Base J, β-D-glucosyl-hydroxymethyluracil, is a modification of thymine DNA base involved in RNA Polymerase (Pol) II transcription termination in kinetoplastid protozoa. Little is understood regarding how specific thymine residues are targeted for J-modification or the mechanism of J regulated transc...

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Bibliographic Details
Main Authors: Rudo Kieft, Yang Zhang, Alexandre P Marand, Jose Dagoberto Moran, Robert Bridger, Lance Wells, Robert J Schmitz, Robert Sabatini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008390

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https://doi.org/10.1371/journal.pgen.1008390

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