Choice of pre-processing pipeline influences clustering quality of scRNA-seq datasets

Abstract Background Single-cell RNA sequencing (scRNA-seq) has quickly become one of the most dominant techniques in modern transcriptome assessment. In particular, 10X Genomics’ Chromium system, with its high throughput approach, turn key and thorough user guide made this cutting-edge technique acc...

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Bibliographic Details
Main Authors: Inbal Shainer, Manuel Stemmer
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07930-6