Authorization of Animal Experiments Is Based on Confidence Rather than Evidence of Scientific Rigor.

Accumulating evidence indicates high risk of bias in preclinical animal research, questioning the scientific validity and reproducibility of published research findings. Systematic reviews found low rates of reporting of measures against risks of bias in the published literature (e.g., randomization...

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Bibliographic Details
Main Authors: Lucile Vogt, Thomas S Reichlin, Christina Nathues, Hanno Würbel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5135031?pdf=render