Evodiamine Mitigates Cellular Growth and Promotes Apoptosis by Targeting the c-Met Pathway in Prostate Cancer Cells

Evodiamine Mitigates Cellular Growth and Promotes Apoptosis by Targeting the c-Met Pathway in Prostate Cancer Cells

Evodiamine (EVO) is an indoloquinazoline alkaloid that exerts its various anti-oncogenic actions by blocking phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt), mitogen-activated protein kinase (MAPK), c-Met, and nuclear factor kappa B (NF-κB) signaling pathways, thus leading to apop...

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Bibliographic Details
Main Authors: Sun Tae Hwang, Jae-Young Um, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Kwang Seok Ahn
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
evodiamine
c-met
stat3
prostate cancer
apoptosis
Online Access:https://www.mdpi.com/1420-3049/25/6/1320

Internet

https://www.mdpi.com/1420-3049/25/6/1320

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