Impact of PD-L1 and PD-1 Expression on the Prognostic Significance of CD8+ Tumor-Infiltrating Lymphocytes in Non-Small Cell Lung Cancer

Impact of PD-L1 and PD-1 Expression on the Prognostic Significance of CD8+ Tumor-Infiltrating Lymphocytes in Non-Small Cell Lung Cancer

The immune infiltrate within tumors has proved to be very powerful in the prognostic stratification of patients and much attention is also being paid towards its predictive value. In this work we therefore aimed at clarifying the significance and impact of PD-L1 and PD-1 expression on the prognostic...

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Bibliographic Details
Main Authors: Enrico Munari, Marcella Marconi, Giulia Querzoli, Gianluigi Lunardi, Pietro Bertoglio, Francesco Ciompi, Alice Tosadori, Albino Eccher, Nicola Tumino, Linda Quatrini, Paola Vacca, Giulio Rossi, Alberto Cavazza, Guido Martignoni, Matteo Brunelli, George J. Netto, Lorenzo Moretta, Giuseppe Zamboni, Giuseppe Bogina
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
PD-L1
PD-1
lung cancer
immunoscore
CD8
TILs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.680973/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.680973/full

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