Respiratory Syncytial Virus F Subunit Vaccine With AS02 Adjuvant Elicits Balanced, Robust Humoral and Cellular Immunity in BALB/c Mice

Respiratory Syncytial Virus F Subunit Vaccine With AS02 Adjuvant Elicits Balanced, Robust Humoral and Cellular Immunity in BALB/c Mice

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory illness, particularly in infants, the elderly, and immunocompromised adults. There is no licensed commercial vaccine against RSV. Importantly, formalin-inactivated RSV vaccines mediate enhanced respiratory disease. RSV fusion...

Full description

Bibliographic Details
Main Authors: Yu Zheng, Lijun Bian, Huiting Zhao, Yulan Liu, Jingcai Lu, Dawei Liu, Ke Zhang, Yueshuang Song, Yusi Luo, Chunlai Jiang, Yan Chen, Yong Zhang, Wei Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
respiratory syncytial virus
subunit vaccine
vaccine adjuvant
humoral immunity
cellular immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.526965/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.526965/full

Similar Items