I-Impute: a self-consistent method to impute single cell RNA sequencing data

I-Impute: a self-consistent method to impute single cell RNA sequencing data

Abstract Background Single-cell RNA-sequencing (scRNA-seq) is becoming indispensable in the study of cell-specific transcriptomes. However, in scRNA-seq techniques, only a small fraction of the genes are captured due to “dropout” events. These dropout events require intensive treatment when analyzin...

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Bibliographic Details
Main Authors: Xikang Feng, Lingxi Chen, Zishuai Wang, Shuai Cheng Li
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Subjects:
scRNA-seq
Imputation
Self-consistency
Cell subpopulation identification
Online Access:http://link.springer.com/article/10.1186/s12864-020-07007-w

Internet

http://link.springer.com/article/10.1186/s12864-020-07007-w

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