Dual Biological Functions of a Cytoprotective Effect and Apoptosis Induction by Bioavailable Marine Carotenoid Fucoxanthinol through Modulation of the Nrf2 Activation in RAW264.7 Macrophage Cells

In this study, the function of fucoxanthinol (FxOH) as a bioavailable marine carotenoid together with the pre-metabolite, fucoxanthin (Fx), was examined through the Nrf2-ARE pathway. The antioxidant activity in the low concentration range of the compounds (1–4 μM) with a peroxyl radical scavenging c...

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Bibliographic Details
Main Authors: Junsei Taira, Miki Sonamoto, Masatsugu Uehara
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Marine Drugs
Subjects:
ESR
Online Access:https://www.mdpi.com/1660-3397/15/10/305