The brain response to peripheral insulin declines with age: a contribution of the blood-brain barrier?

<h4>Objectives</h4>It is a matter of debate whether impaired insulin action originates from a defect at the neural level or impaired transport of the hormone into the brain. In this study, we aimed to investigate the effect of aging on insulin concentrations in the periphery and the cent...

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Bibliographic Details
Main Authors: Tina Sartorius, Andreas Peter, Martin Heni, Walter Maetzler, Andreas Fritsche, Hans-Ulrich Häring, Anita M Hennige
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126804