CLDN6 promotes chemoresistance through GSTP1 in human breast cancer

CLDN6 promotes chemoresistance through GSTP1 in human breast cancer

Abstract Background Claudin-6 (CLDN6), a member of CLDN family and a key component of tight junction, has been reported to function as a tumor suppressor in breast cancer. However, whether CLDN6 plays any role in breast cancer chemoresistance remains unclear. In this study, we investigated the role...

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Bibliographic Details
Main Authors: Minlan Yang, Yanru Li, Xiangfeng Shen, Yang Ruan, Yan Lu, Xiangshu Jin, Peiye Song, Yantong Guo, Xiaoli Zhang, Huinan Qu, Yijia Shao, Chengshi Quan
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
CLDN6
Chemoresistance
GSTP1
p53
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s13046-017-0627-9

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http://link.springer.com/article/10.1186/s13046-017-0627-9

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