Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells

Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells

The purpose of this study was to devise a strategy for the derivation of corneal endothelial cells (CEnCs) from adult fibroblast-derived induced pluripotent stem cells (iPSCs). IPSCs were generated from an adult human with normal ocular history via expression of OCT4, SOX2, KLF4 and c-MYC. Neural cr...

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Bibliographic Details
Main Authors: Michael D. Wagoner, Laura R. Bohrer, Benjamin T. Aldrich, Mark A. Greiner, Robert F. Mullins, Kristan S. Worthington, Budd A. Tucker, Luke A. Wiley
Format: Article
Language:English
Published: The Company of Biologists 2018-05-01
Series:Biology Open
Subjects:
Induced pluripotent stem cells
Differentiation
Neural crest cells
Corneal endothelial cells
Online Access:http://bio.biologists.org/content/7/5/bio032102

Internet

http://bio.biologists.org/content/7/5/bio032102

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