Integrating signals from the T-cell receptor and the interleukin-2 receptor.

Integrating signals from the T-cell receptor and the interleukin-2 receptor.

T cells orchestrate the adaptive immune response, making them targets for immunotherapy. Although immunosuppressive therapies prevent disease progression, they also leave patients susceptible to opportunistic infections. To identify novel drug targets, we established a logical model describing T-cel...

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Bibliographic Details
Main Authors: Tilo Beyer, Mandy Busse, Kroum Hristov, Slavyana Gurbiel, Michal Smida, Utz-Uwe Haus, Kathrin Ballerstein, Frank Pfeuffer, Robert Weismantel, Burkhart Schraven, Jonathan A Lindquist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3150289?pdf=render

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http://europepmc.org/articles/PMC3150289?pdf=render

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