<i>In Vitro</i> and <i>In Silico</i> Approaches for the Antileishmanial Activity Evaluations of Actinomycins Isolated from Novel <i>Streptomyces smyrnaeus</i> Strain UKAQ_23

<i>In Vitro</i> and <i>In Silico</i> Approaches for the Antileishmanial Activity Evaluations of Actinomycins Isolated from Novel <i>Streptomyces smyrnaeus</i> Strain UKAQ_23

Leishmaniasis, a Neglected Tropical Parasitic Disease (NTPD), is induced by several <i>Leishmania</i> species and is disseminated through sandfly (<i>Lutzomyia longipalpis</i>) bites. The parasite has developed resistance to currently prescribed antileishmanial drugs, and it...

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Bibliographic Details
Main Authors: Kamal A. Qureshi, Ibrahim Al Nasr, Waleed S. Koko, Tariq A. Khan, M. Qaiser Fatmi, Mahrukh Imtiaz, Riaz A. Khan, Hamdoon A. Mohammed, Mariusz Jaremko, Abdul-Hamid Emwas, Faizul Azam, Avinash D. Bholay, Gamal O. Elhassan, Dinesh K. Prajapati
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Antibiotics
Subjects:
actinomycin X<sub>2</sub>
actinomycin D
<i>in silico</i> molecular modeling
Kala-azar
leishmaniasis
molecular dynamics simulation
Online Access:https://www.mdpi.com/2079-6382/10/8/887

Internet

https://www.mdpi.com/2079-6382/10/8/887

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