δ-Tocotrienol suppresses tumorigenesis by inducing apoptosis and blocking the COX-2/PGE2 pathway that stimulates tumor–stromal interactions in colon cancer

Anticancer effects of δ-tocotrienol have been reported for several types of cancer, but have not been fully elucidated in colorectal cancer. We investigated the anti-proliferative effect of tocotrienols in vitro, in colon epithelial cells and stromal cells, and in vivo, in an induced colorectal canc...

Full description

Bibliographic Details
Main Authors: S. Wada, Y. Naito, Y. Matsushita, M. Nouchi, M. Kawai, E. Minami, W. Aoi, S. Ikeda, A. Higashi, T. Yoshikawa
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617303183