Hepatocyte Transplantation in the Long Evans Cinnamon Rat Model of Wilson's Disease

Wilson's disease (WD), caused by a mutation in the P-type copper transporting ATPase (Atp7b) gene, results in excessive accumulation of copper in the liver. Long Evans Cinnamon rats (LEC) bear a mutation in the atp7b gene and share clinical characteristics of human WD. To explore hepatocyte tra...

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Bibliographic Details
Main Authors: Seon Mee Park, Kim Vo, Michel Lallier, Alexis-Simon Cloutier, Pierre Brochu, Fernando Alvarez, Steven R. Martin
Format: Article
Language:English
Published: SAGE Publishing 2006-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000006783982188