Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx<sup>®</sup>) or vincristine

Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx<sup>®</sup>) or vincristine

<p>Abstract</p> <p>Background</p> <p>Chemotherapy for glioblastoma (GBM) patients is compromised in part by poor perfusion in the tumor. The present study evaluates how treatment with liposomal formulation of irinotecan (Irinophore C™), and other liposomal anticancer dr...

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Bibliographic Details
Main Authors: Waterhouse Dawn, Kozlowski Piotr, Yung Andrew, Anantha Malathi, Masin Dana, Strutt Dita, Verreault Maite, Bally Marcel B, Yapp Donald T
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Cancer
Subjects:
glioblastoma multiforme
vasculature normalization
liposomal drugs
endothelial cells
Online Access:http://www.biomedcentral.com/1471-2407/11/124

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http://www.biomedcentral.com/1471-2407/11/124

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