The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma

The Combination Therapy of Dietary Galacto-Oligosaccharides With Budesonide Reduces Pulmonary Th2 Driving Mediators and Mast Cell Degranulation in a Murine Model of House Dust Mite Induced Asthma

Background: Dietary non-digestible galacto-oligosaccharides (GOS) suppress allergic responses in mice sensitized and challenged with house dust mite (HDM). Budesonide is the standard therapy for allergic asthma in humans but is not always completely effective.Aim: To compare the efficacy of budesoni...

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Bibliographic Details
Main Authors: Kim A. T. Verheijden, Saskia Braber, Thea Leusink-Muis, Prescilla V. Jeurink, Suzan Thijssen, Aletta D. Kraneveld, Johan Garssen, Gert Folkerts, Linette E. M. Willemsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
allergy
asthma
house dust mite
galacto-oligosaccharides
budesonide
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02419/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02419/full

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