The role of SIRT1 in diabetic kidney disease

Sirtuins (SIRTs) are members of the silent information regulator 2 (Sir2) family. In mammals, of the seven known SIRTs, SIRT1 function is most studied and has been shown to regulate wide range of cellular functions that affect metabolic homeostasis and aging. SIRT1 exerts anti-apoptotic, anti-oxidat...

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Bibliographic Details
Main Authors: Rabi eYacoub, Kyung eLee, John Cijiang He
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00166/full