Purinergic Cooperation Between P2Y2 and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes

Purinergic Cooperation Between P2Y2 and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes

The release of damage-associated molecular patterns, including uridine triphosphate (UTP) and adenosine triphosphate (ATP) to the extracellular milieu is a key component of innate immune response to infection. Previously, we showed that macrophage infection by the protozoan parasite Leishmania amazo...

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Bibliographic Details
Main Authors: Maria Luiza Thorstenberg, Marcos Vinícius Rangel Ferreira, Natália Amorim, Claudio Canetti, Fernanda B. Morrone, José Carlos Alves Filho, Robson Coutinho-Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
Leishmania amazonensis
LTB4
PANX-1
P2Y2
P2X7
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01531/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01531/full

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