Regulation of virulence gene expression resulting from Streptococcus pneumoniae and nontypeable Haemophilus influenzae interactions in chronic disease.

Chronic rhinosinusitis (CRS) is a common inflammatory disease of the sinonasal cavity mediated, in part, by polymicrobial communities of bacteria. Recent molecular studies have confirmed the importance of Streptococcus pneumoniae and nontypeable Haemophilus influenzae (NTHi) in CRS. Here, we hypothe...

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Main Authors: Emily K Cope, Natalia Goldstein-Daruech, Jennifer M Kofonow, Lanette Christensen, Bridget McDermott, Fernando Monroy, James N Palmer, Alexander G Chiu, Mark E Shirtliff, Noam A Cohen, Jeff G Leid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3230614?pdf=render