A single-cell survey of cellular hierarchy in acute myeloid leukemia

A single-cell survey of cellular hierarchy in acute myeloid leukemia

Abstract Background Acute myeloid leukemia (AML) is a fatal hematopoietic malignancy and has a prognosis that varies with its genetic complexity. However, there has been no appropriate integrative analysis on the hierarchy of different AML subtypes. Methods Using Microwell-seq, a high-throughput sin...

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Bibliographic Details
Main Authors: Junqing Wu, Yanyu Xiao, Jie Sun, Huiyu Sun, Haide Chen, Yuanyuan Zhu, Huarui Fu, Chengxuan Yu, Weigao E., Shujing Lai, Lifeng Ma, Jiaqi Li, Lijiang Fei, Mengmeng Jiang, Jingjing Wang, Fang Ye, Renying Wang, Ziming Zhou, Guodong Zhang, Tingyue Zhang, Qiong Ding, Zou Wang, Sheng Hao, Lizhen Liu, Weiyan Zheng, Jingsong He, Weijia Huang, Yungui Wang, Jin Xie, Tiefeng Li, Tao Cheng, Xiaoping Han, He Huang, Guoji Guo
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Hematology & Oncology
Subjects:
Acute myeloid leukemia
Single-cell mRNA sequencing
Microwell-seq
Ribosomal protein
Single-molecule real-time sequencing
Cancer attractor
Online Access:http://link.springer.com/article/10.1186/s13045-020-00941-y

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http://link.springer.com/article/10.1186/s13045-020-00941-y

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