Milligram production and biological activity characterization of the human chemokine receptor CCR3.

Human chemokine receptor CCR3 (hCCR3) belongs to the G protein-coupled receptors (GPCRs) superfamily of membrane proteins and plays major roles in allergic diseases and angiogenesis. In order to study the structural and functional mechanism of hCCR3, it is essential to produce pure protein with biol...

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Bibliographic Details
Main Authors: Mingqing Wang, Baosheng Ge, Renmin Li, Xiaoqiang Wang, Jun Lao, Fang Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3670934?pdf=render