Postreplication Roles of the Brucella VirB Type IV Secretion System Uncovered via Conditional Expression of the VirB11 ATPase

Brucella abortus, the bacterial agent of the worldwide zoonosis brucellosis, primarily infects host phagocytes, where it undergoes an intracellular cycle within a dedicated membrane-bound vacuole, the Brucella-containing vacuole (BCV). Initially of endosomal origin (eBCV), BCVs are remodeled into re...

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Bibliographic Details
Main Authors: Erin P. Smith, Cheryl N. Miller, Robert Child, Jennifer A. Cundiff, Jean Celli
Format: Article
Language:English
Published: American Society for Microbiology 2016-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/7/6/e01730-16