Bacterial toxin effector membrane targeting: Outside in, then back again.

Pathogenic bacteria utilize multiple approaches to mediate their toxicity to eukaryotic cells. Dedicated protein machines deposit toxic effectors directly inside the host, whereas secreted toxins must enter cells independently of other bacterial components. Regardless of how they reach the cytosol...

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Bibliographic Details
Main Author: Brett eGeissler
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00075/full