Bmi1 is required for hepatic progenitor cell expansion and liver tumor development.

Bmi1 is required for hepatic progenitor cell expansion and liver tumor development.

Bmi1 is a polycomb group transcriptional repressor and it has been implicated in regulating self-renewal and proliferation of many types of stem or progenitor cells. In addition, Bmi1 has been shown to function as an oncogene in multiple tumor types. In this study, we investigated the functional sig...

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Bibliographic Details
Main Authors: Lingling Fan, Chuanrui Xu, Chunmei Wang, Junyan Tao, Coral Ho, Lijie Jiang, Bing Gui, Shiang Huang, Matthias Evert, Diego F Calvisi, Xin Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460872?pdf=render

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http://europepmc.org/articles/PMC3460872?pdf=render

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