Preclinical Testing of Living Tissue-Engineered Heart Valves for Pediatric Patients, Challenges and Opportunities

Preclinical Testing of Living Tissue-Engineered Heart Valves for Pediatric Patients, Challenges and Opportunities

Introduction: Pediatric patients with cardiac congenital diseases require heart valve implants that can grow with their natural somatic increase in size. Current artificial valves perform poorly in children and cannot grow; thus, living-tissue-engineered valves capable of sustaining matrix homeostas...

Full description

Bibliographic Details
Main Authors: Ionela Movileanu, Marius Harpa, Hussam Al Hussein, Lucian Harceaga, Alexandru Chertes, Hamida Al Hussein, Georg Lutter, Thomas Puehler, Terezia Preda, Carmen Sircuta, Ovidiu Cotoi, Dan Nistor, Adrian Man, Bogdan Cordos, Radu Deac, Horatiu Suciu, Klara Brinzaniuc, Megan Casco, Leslie Sierad, Margarita Bruce, Dan Simionescu, Agneta Simionescu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
acellular scaffolds
autologous cells
bioreactor conditioning
orthotopic implantation
cell seeding
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.707892/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2021.707892/full

Similar Items