AT-406, an IAP Inhibitor, Activates Apoptosis and Induces Radiosensitization of Normoxic and Hypoxic Cervical Cancer Cells

AT-406, an IAP Inhibitor, Activates Apoptosis and Induces Radiosensitization of Normoxic and Hypoxic Cervical Cancer Cells

IAP antagonists increased the antitumor efficacy of X-irradiation in some types of cancers, but their effects on hypoxic cancer cells remain unclarified. We aims to investigate the radiosensitizing effect of an IAP inhibitor AT-406 on cervical cancer cell lines under both normoxia and hypoxia condit...

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Bibliographic Details
Main Authors: Jing Lu, Qin Qin, Liang-Liang Zhan, Jia Liu, Hong-Cheng Zhu, Xi Yang, Chi Zhang, Li-Ping Xu, Zhe-Ming Liu, Di Wang, He-Qing Cui, Ciu-Ciu Meng, Jing Cai, Hong-Yan Cheng, Xin-Chen Sun
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319300477

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http://www.sciencedirect.com/science/article/pii/S1347861319300477

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