Histone deacetylase inhibitors – molecular mechanisms of actions and clinical applications
Histone deacetylases (HDACs) play an important role in the epigenetic regulation of gene expression implicated in cancer pathogenesis. Inhibitors of HDACs (HDI) are under investigation as novel anti-cancer drugs, which induce histone hyperacetylation. These agents modulate chromatin structure leadin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Index Copernicus International S.A.
2013-08-01
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| Series: | Postępy Higieny i Medycyny Doświadczalnej |
| Subjects: | |
| Online Access: | http://journals.indexcopernicus.com/fulltxt.php?ICID=1061381 |