The Rickettsial Ankyrin Repeat Protein 2 Is a Type IV Secreted Effector That Associates with the Endoplasmic Reticulum

Strains of Rickettsia rickettsii, the tick-borne agent of Rocky Mountain spotted fever, vary considerably in virulence. Genomic comparisons of R. rickettsii strains have identified a relatively small number of genes divergent in an avirulent strain. Among these is one annotated as Rickettsia ankyrin...

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Main Authors: Stephanie S. Lehman, Nicholas F. Noriea, Karin Aistleitner, Tina R. Clark, Cheryl A. Dooley, Vinod Nair, Simran Jeet Kaur, M. Sayeedur Rahman, Joseph J. Gillespie, Abdu F. Azad, Ted Hackstadt
Format: Article
Language:English
Published: American Society for Microbiology 2018-06-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.00975-18