Piceatannol, a natural analogue of resveratrol, effectively reduces beta-amyloid levels via activation of alpha-secretase and matrix metalloproteinase-9

Piceatannol, a natural analogue of resveratrol, effectively reduces beta-amyloid levels via activation of alpha-secretase and matrix metalloproteinase-9

Beta-amyloid (Aβ) is a major pathogenic molecule in Alzheimer's disease (AD). The mechanisms of Aβ reduction by resveratrol and its analogues, oxyresveratrol and piceatannol were investigated through examination of amyloid precursor protein (APP) processing and Aβ degradation enzyme activities....

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Bibliographic Details
Main Authors: Boyoung Choi, Suyeon Kim, Bong-Geum Jang, Min-Ju Kim
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Journal of Functional Foods
Subjects:
Alzheimer's disease
Beta-amyloid
Resveratrol
Piceatannol
Secretase
Beta-amyloid degradation enzyme
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616000803

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http://www.sciencedirect.com/science/article/pii/S1756464616000803

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