Structural Basis for Capsid Recruitment and Coat Formation during HSV-1 Nuclear Egress

During herpesvirus infection, nascent viral capsids egress the nucleus into the cytoplasm by an unusual mechanism whereby capsids bud at the inner nuclear membrane. This process is mediated by the conserved heterodimeric nuclear egress complex (NEC), anchored to the inner nuclear membrane, that defo...

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Bibliographic Details
Main Authors: Elizabeth Draganova, Jiayan Zhang, Hong Zhou, Ekaterina Heldwein
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
Online Access:https://www.mdpi.com/2504-3900/50/1/101