Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance

Abstract Background Myopia (short-sightedness) affects approximately 1.4 billion people worldwide, and prevalence is increasing. Animal models induced by defocusing lenses show striking similarity with human myopia in terms of morphology and the implicated genetic pathways. Less is known about prote...

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Bibliographic Details
Main Authors: Nina Riddell, Pierre Faou, Sheila G. Crewther
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Developmental Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12861-018-0177-1