Loss of Function SETD2 Mutations in Poorly Differentiated Metastases from Two Hürthle Cell Carcinomas of the Thyroid

Loss of Function SETD2 Mutations in Poorly Differentiated Metastases from Two Hürthle Cell Carcinomas of the Thyroid

Hürthle cell carcinomas (HCC) are rare differentiated thyroid cancers that display low avidity for radioactive iodine and respond poorly to kinase inhibitors. Here, using next-generation sequencing, we analyzed the mutational status of primary tissue and poorly differentiated metastatic tissue from...

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Bibliographic Details
Main Authors: Valeria Pecce, Antonella Verrienti, Luana Abballe, Raffaella Carletti, Giorgio Grani, Rosa Falcone, Valeria Ramundo, Cosimo Durante, Cira Di Gioia, Diego Russo, Sebastiano Filetti, Marialuisa Sponziello
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
SETD2 loss-of-function mutations
Hürthle cell carcinoma
poorly differentiated thyroid cancer
Online Access:https://www.mdpi.com/2072-6694/12/7/1892

Internet

https://www.mdpi.com/2072-6694/12/7/1892

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