Full versus half dose of antenatal betamethasone to prevent severe neonatal respiratory distress syndrome associated with preterm birth: study protocol for a randomised, multicenter, double blind, placebo-controlled, non-inferiority trial (BETADOSE)

Full versus half dose of antenatal betamethasone to prevent severe neonatal respiratory distress syndrome associated with preterm birth: study protocol for a randomised, multicenter, double blind, placebo-controlled, non-inferiority trial (BETADOSE)

Abstract Background Although antenatal betamethasone is recommended worldwide for women at risk of preterm delivery, concerns persist regarding the long-term effects associated with this treatment. Indeed, adverse events, mainly dose-related, have been reported. The current recommended dose of anten...

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Bibliographic Details
Main Authors: Thomas Schmitz, Corinne Alberti, Moreno Ursino, Olivier Baud, Camille Aupiais, for the BETADOSE study group and the GROG (Groupe de Recherche en Gynécologie Obstétrique)
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Pregnancy and Childbirth
Subjects:
Antenatal betamethasone
Antenatal corticosteroids
Preterm delivery
Preterm birth
Respiratory distress syndrome
Non-inferiority
Online Access:http://link.springer.com/article/10.1186/s12884-019-2206-x

Internet

http://link.springer.com/article/10.1186/s12884-019-2206-x

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