Metabolomics analysis of plasma and adipose tissue samples from mice orally administered with polydextrose and correlations with cecal microbiota

Abstract Polydextrose (PDX) is a branched glucose polymer, utilized as a soluble dietary fiber. Recently, PDX was found to have hypolipidemic effects and effects on the gut microbiota. To investigate these findings more closely, a non-targeted metabolomics approach, was exploited to determine metabo...

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Bibliographic Details
Main Authors: Markku Tapani Saarinen, Olli Kärkkäinen, Kati Hanhineva, Kirsti Tiihonen, Ashley Hibberd, Kari Antero Mäkelä, Ghulam Shere Raza, Karl-Heinz Herzig, Heli Anglenius
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78484-y