Upregulated Talin1 synergistically boosts β-estradiol-induced proliferation and pro-angiogenesis of eutopic and ectopic endometrial stromal cells in adenomyosis

Upregulated Talin1 synergistically boosts β-estradiol-induced proliferation and pro-angiogenesis of eutopic and ectopic endometrial stromal cells in adenomyosis

Abstract Adenomyosis (ADS) is an estrogen-dependent gynecological disease with unspecified etiopathogenesis. Local hyperestrogenism may serve a key role in contributing to the origin of ADS. Talin1 is mostly identified to be overexpressed and involved in the progression of numerous human carcinomas...

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Bibliographic Details
Main Authors: Yi-yi Wang, Hua Duan, Sha Wang, Yong-jun Quan, Jun-hua Huang, Zheng-chen Guo
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
Adenomyosis (ADS)
β-Estradiol (β-E2)
Talin1
Adenomyotic eutopic and ectopic endometrial stromal cell (ADS_Eu_ESC and ADS_Ec_ESC)
Proliferation
Pro-angiogenesis
Online Access:https://doi.org/10.1186/s12958-021-00756-7

Internet

https://doi.org/10.1186/s12958-021-00756-7

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