Syndecans as modulators and potential pharmacological targets in cancer progression

Syndecans as modulators and potential pharmacological targets in cancer progression

Extracellular matrix (ECM) components form a dynamic network of key importance for cell function and properties. Key macromolecules in this interplay are syndecans (SDCs), a family of transmembrane heparan sulfate proteoglycans (HSPGs). Specifically, heparan sulfate (HS) chains with their different...

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Bibliographic Details
Main Authors: Despoina eBarbouri, Nikolaos eAfratis, Chrisostomi eGialeli, Demitrios H Vynios, Achilleas D Theocharis, Nikos eKaramanos
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Oncology
Subjects:
Proteoglycans
Syndecans
Tumor Microenvironment
Cancer
Heparan sulfate
shed syndecans
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00004/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00004/full

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