Genetic Modulation of Initial Sensitivity to Δ9-Tetrahydrocannabinol (THC) Among the BXD Family of Mice

Genetic Modulation of Initial Sensitivity to Δ9-Tetrahydrocannabinol (THC) Among the BXD Family of Mice

Cannabinoid receptor 1 activation by the major psychoactive component in cannabis, Δ9-tetrahydrocannabinol (THC), produces motor impairments, hypothermia, and analgesia upon acute exposure. In previous work, we demonstrated significant sex and strain differences in acute responses to THC following a...

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Bibliographic Details
Main Authors: Cory Parks, Chris M. Rogers, Pjotr Prins, Robert W. Williams, Hao Chen, Byron C. Jones, Bob M. Moore, Megan K. Mulligan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
C57BL/6
DBA/2
THC
BXD family
cannabis
addiction
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.659012/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.659012/full

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