Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation

Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation

Neural stem cells (NSCs) have the potential to generate the cells of the nervous system and, when cultured on nanofiber scaffolds, constitute a promising approach for neural tissue engineering. In this work, the impact of combining nanofiber alignment with functionalization of the electrospun poly-ε...

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Bibliographic Details
Main Authors: Miriam C. Amores de Sousa, Carlos A. V. Rodrigues, Inês A. F. Ferreira, Maria Margarida Diogo, Robert J. Linhardt, Joaquim M. S. Cabral, Frederico Castelo Ferreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
PCL
functionalization
nanofibers
electrospinning
neural stem cells
laminin
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.580135/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.580135/full

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