Biologically active pigment and ShlA cytolysin of Serratia marcescens induce autophagy in a human ocular surface cell line

Abstract Background The cellular process of autophagy is essential for maintaining the health of ocular tissue. Dysregulation of autophagy is associated with several ocular diseases including keratoconus and macular degeneration. It is known that autophagy can be used to respond to microbial infecti...

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Bibliographic Details
Main Authors: Kimberly M. Brothers, Nicholas A. Stella, Robert M. Q. Shanks
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Ophthalmology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12886-020-01387-z