Ellagic Acid Activated PPAR Signaling Pathway to Protect Ileums Against Castor Oil-Induced Diarrhea in Mice: Application of Transcriptome Analysis in Drug Screening

Ellagic Acid Activated PPAR Signaling Pathway to Protect Ileums Against Castor Oil-Induced Diarrhea in Mice: Application of Transcriptome Analysis in Drug Screening

BackgroundAcute diarrhea is still a common and serious disease. The causes of acute diarrhea are very complicated. Therefore, we need to find a medicine to control diarrhea symptoms, save time for diagnosis of pathogens, and prevent drug abuse. Ellagic acid (EA), a natural polyphenol drug, has anti-...

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Bibliographic Details
Main Authors: Jianqing Chen, Hongliang Yang, Zunlai Sheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
ellagic acid
transcriptome
PPAR signaling pathway
castor oil
diarrhea
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01681/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01681/full

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