Maternal valacyclovir and infant cytomegalovirus acquisition: a randomized controlled trial among HIV-infected women.

Studies in HIV-1-infected infants and HIV-1-exposed, uninfected infants link early cytomegalovirus (CMV) acquisition with growth delay and cognitive impairment. We investigated maternal valacyclovir to delay infant acquisition of CMV.Pregnant women with HIV-1, HSV-2 and CD4 count >250 cells/µl we...

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Main Authors: Alison C Roxby, Claire Atkinson, Kristjana Asbjörnsdóttir, Carey Farquhar, James N Kiarie, Alison L Drake, Anna Wald, Michael Boeckh, Barbra Richardson, Vincent Emery, Grace John-Stewart, Jennifer A Slyker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913686?pdf=render