Distinct Residential and Infiltrated Macrophage Populations and Their Phagocytic Function in Mild and Severe Neonatal Hypoxic-Ischemic Brain Damage

Distinct Residential and Infiltrated Macrophage Populations and Their Phagocytic Function in Mild and Severe Neonatal Hypoxic-Ischemic Brain Damage

Neonatal brain injury, especially severe injury induced by hypoxia-ischemia (HI), causes mortality and long-term neurological impairments. Our previous study demonstrated activation of CD11b+ myeloid cells, including residential microglial cells (MGs) and infiltrating monocyte-derived macrophages (M...

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Bibliographic Details
Main Authors: Yingjun Min, Lin Yan, Qian Wang, Fang Wang, Hairong Hua, Yun Yuan, Huiyan Jin, Ming Zhang, Yaling Zhao, Jianzhong Yang, Xiangning Jiang, Yuan Yang, Fan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
hypoxia
ischemia
microglia
monocyte-derived macrophages
phagocytosis
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00244/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00244/full

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