Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms

Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms

An important aspect of Huntington's disease (HD) pathogenesis which may have important therapeutic implications is that the cellular events leading to cell death may be different in cortical and striatal neurons. In the present study, we characterized cellular changes in cortical and striatal n...

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Bibliographic Details
Main Authors: Marie-Christine Galas, Nicolas Bizat, Laetitia Cuvelier, Kadiombo Bantubungi, Emmanuel Brouillet, Serge N Schiffmann, David Blum
Format: Article
Language:English
Published: Elsevier 2004-02-01
Series:Neurobiology of Disease
Subjects:
Cell death
Huntington's disease
3-Nitropropionic acid
Apoptosis
Cortex
Striatum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103002006

Internet

http://www.sciencedirect.com/science/article/pii/S0969996103002006

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