Effect of L-DOPA/Benserazide on Propagation of Pathological α-Synuclein

Parkinson’s disease (PD) and related disorders are characterized by filamentous or fibrous structures consisting of abnormal α-synuclein in the brains of patients, and the distributions and spread of these pathologies are closely correlated with disease progression. L-DOPA (a dopamine precursor) is...

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Bibliographic Details
Main Authors: Aki Shimozawa, Yuuki Fujita, Hiromi Kondo, Yu Takimoto, Makoto Terada, Masanao Sanagi, Shin-ichi Hisanaga, Masato Hasegawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00595/full