Calreticulin and Galectin-3 Opsonise Bacteria for Phagocytosis by Microglia

Opsonins are soluble, extracellular proteins, released by activated immune cells, and when bound to a target cell, can induce phagocytes to phagocytose the target cell. There are three known classes of opsonin: antibodies, complement factors and secreted pattern recognition receptors, but these have...

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Bibliographic Details
Main Authors: Tom O. J. Cockram, Mar Puigdellívol, Guy C. Brown
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02647/full